Keto Spicy Pepper Jack Chicken Casserole is a creamy, cheesy, low-carb dinner loaded with tender chicken, spicy pepper jack, and fresh jalapeños for a perfect kick. This Keto Spicy Pepper Jack Chicken Casserole recipe delivers quick prep, bold flavor, and the ideal easy weeknight meal for anyone eating keto.

About This Recipe

This Keto Spicy Pepper Jack Chicken Casserole is designed for anyone who wants a fast, flavor-packed dinner that still feels comforting and satisfying while staying fully low carb. The combination of juicy shredded chicken, melty pepper jack cheese, cream cheese, and green chiles creates a creamy base with just the right level of heat. It’s a dish that feels indulgent without ever leaving keto territory, and the layered flavors make it taste far more complex than the simple prep suggests.

The casserole bakes into a bubbly, cheesy top while the inside becomes unbelievably creamy—exactly the kind of texture people crave from a classic American comfort casserole, but without the pasta, flour, or starches that normally push carbs through the roof. The jalapeños add freshness and mild spice, but the heat can be tuned up or down depending on personal preference. Even those who don’t usually love spicy food tend to enjoy this one because the cream cheese and chicken mellow the kick, keeping everything balanced.

One of the biggest advantages of this recipe is that it’s perfect for busy weeknights. You can use rotisserie chicken, leftover chicken breast, or meal-prepped shredded chicken to make things even faster. Everything mixes in one bowl, goes into a baking dish, and bakes into a bubbling casserole that tastes like you spent far more time on it than you actually did. The leftovers reheat beautifully and make an ideal lunch for the next day, keeping you full for hours thanks to the high-protein and high-fat keto combination.

Whether you’re feeding family, meal prepping for the week, or prepping a reliable low-carb dish for your routine, this casserole checks every box. It delivers bold flavor, creamy texture, and effortless assembly while staying firmly keto. It’s the kind of go-to recipe you’ll return to again and again whenever you want something comforting, spicy, and incredibly easy.

Why You’ll Love This Recipe

One-bowl prep and minimal cleanup
Creamy, cheesy, spicy flavor without the carbs
Uses rotisserie or leftover chicken
Perfect for weekly meal prep
Customizable heat level
Family-friendly comfort food
Reheats well without drying out

Ingredients

3 cups cooked shredded chicken
1 cup pepper jack cheese, shredded
4 oz cream cheese, softened
1 cup shredded cheddar cheese
1/2 cup sour cream
1 can (4 oz) diced green chiles
1 jalapeño, seeded and diced
1/2 tsp garlic powder
1/2 tsp onion powder
Salt and pepper, to taste

Instructions

Preheat oven to 375°F.
In a large bowl, mix cream cheese, sour cream, green chiles, jalapeño, garlic powder, onion powder, salt, and pepper.
Stir in shredded chicken and pepper jack cheese until fully combined.
Transfer mixture to a greased baking dish.
Top with shredded cheddar cheese.
Bake 20–25 minutes, or until hot and bubbly.
Let rest 5 minutes before serving.

Nutrition (per serving)

Calories: ~420
Fat: 30g
Protein: 33g
Net Carbs: 4g

FAQ

Can I use chicken thighs instead?
Yes, they work perfectly and stay extra juicy.
Is this dish very spicy?
The heat is mild, but you can remove seeds or adjust jalapeños.
Can I make this dairy-free?
Not recommended; the sauce depends on cheese and cream.
Does it reheat well?
Yes, the sauce thickens slightly but reheats creamy.
Can I freeze it?
Freezing is possible, but dairy may separate slightly.
What sides go best with it?
Cauliflower rice or sautéed veggies keep it keto.

Variations & Substitutions

Swap cheddar for Monterey Jack
Add cooked bacon for extra richness
Use canned jalapeño slices for stronger heat
Add sautéed bell peppers for flavor without carbs
Use rotisserie chicken for fastest prep

Serving Suggestions

Serve over cauliflower rice
Pair with a simple green salad
Add sautéed zucchini on the side

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